L-Thyroxine Therapy for Older Adults With Subclinical #Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial

..132 participants had Hypothyroid Symptoms scores greater than 30, and 133 had Tiredness scores greater than 40. Among the group with high symptom burden, the Hypothyroid Symptoms score improved similarly between those receiving L-thyroxine (mean within-group change, −12.3 [95% CI, −16.6 to −8.0]) and those receiving placebo (mean within-group change, −10.4 [CI, −15.3 to −5.4]) at 1 year; the adjusted between-group difference was −2.0 (CI, … Continue reading L-Thyroxine Therapy for Older Adults With Subclinical #Hypothyroidism and Hypothyroid Symptoms: Secondary Analysis of a Randomized Trial

A Comparison of Biomarker Rise in Type 1 and Type 2 Myocardial Infarction

..Type 1 myocardial infarction tended to be larger than type 2 myocardial infarction, with a significantly higher mean percentage rise for both cTnT and CK-MB as well as higher mean RULN (207 vs 86 for cTnT, P = 0.02; 9 vs 4 for CK-MB, P = 0.002). There was a trend toward a higher rise of cTnT than CK-MB in type 2 compared with type … Continue reading A Comparison of Biomarker Rise in Type 1 and Type 2 Myocardial Infarction