Day: Apr 9, 2020

Environment, Infectivology

Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of #Coronavirus Disease 2019 in Wuhan, China

..The median age of the cases was 57 years and 50.3% were women. The attack rate peaked in the third period and substantially declined afterwards across geographic regions, sex and age groups, except for children (age <20) whose attack rate continued to increase. Healthcare workers and elderly people had higher attack rates and severity risk increased with age. The effective reproductive number dropped from 3.86 … Continue reading Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of #Coronavirus Disease 2019 in Wuhan, China

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Diet, Infectivology, Nephrology

A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation

The Western diet is rich in salt, which poses various health risks. A high-salt diet (HSD) can stimulate immunity through the nuclear factor of activated T cells 5 (Nfat5)–signaling pathway, especially in the skin, where sodium is stored. The kidney medulla also accumulates sodium to build an osmotic gradient for water conservation. Here, we studied the effect of an HSD on the immune defense against … Continue reading A high-#salt diet compromises antibacterial neutrophil responses through hormonal perturbation

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