A Randomized, Controlled Trial of #Liraglutide for Adolescents with #Obesity

Liraglutide was superior to placebo with regard to the change from baseline in the BMI standard-deviation score at week 56 (estimated difference, −0.22; 95% confidence interval [CI], −0.37 to −0.08; P=0.002). A reduction in BMI of at least 5% was observed in 51 of 113 participants in the liraglutide group and in 20 of 105 participants in the placebo group (estimated percentage, 43.3% vs. 18.7%), … Continue reading A Randomized, Controlled Trial of #Liraglutide for Adolescents with #Obesity

Loss of life expectancy from air #pollution compared to other risk factors: a worldwide perspective

..We used a data-informed atmospheric model to calculate worldwide exposure to PM2.5 and ozone pollution, which was combined with the GEMM to estimate disease-specific excess mortality and loss of life expectancy (LLE) in 2015. Using this model, we investigated the effects of different pollution sources, distinguishing between natural (wildfires, aeolian dust) and anthropogenic emissions, including fossil fuel use. Global excess mortality from all ambient air … Continue reading Loss of life expectancy from air #pollution compared to other risk factors: a worldwide perspective