Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

Recent discoveries have implicated the gut #microbiome in the progression and severity of #Parkinson’s disease; however, how gut bacteria affect such neurodegenerative disorders remains unclear. Here, we report that the Bacillus subtilis probiotic strain PXN21 inhibits α-synuclein aggregation and clears preformed aggregates in an established Caenorhabditis elegans model of synucleinopathy. This protection is seen in young and aging animals and is partly mediated by DAF-16. … Continue reading Probiotic Bacillus subtilis Protects against α-Synuclein Aggregation in C. elegans

Effects of physical activity #calorie equivalent food labelling to reduce food selection and consumption: systematic review and meta-analysis of randomised controlled studies

There is limited evidence that nutritional labelling on food/drinks is changing eating behaviours. Physical activity calorie equivalent (PACE) food labelling aims to provide the public with information about the amount of physical activity required to expend the number of kilocalories in food/drinks (eg, calories in this pizza requires 45 min of running to burn), to encourage healthier food choices and reduce disease.. ..When PACE labelling was … Continue reading Effects of physical activity #calorie equivalent food labelling to reduce food selection and consumption: systematic review and meta-analysis of randomised controlled studies