Sex Steroid #Hormones and #Asthma in a Nationwide Study of U.S. Adults

Women have a higher burden of asthma than men. Although sex hormones may explain sex differences in asthma, their role is unclear.. ..Free testosterone levels in the fourth quartile were associated with lower odds of current asthma in women (odds ratio [OR] for the fourth quartile [Q4] vs. Q1, 0.56; 95% confidence interval [CI], 0.39–0.80). Given an interaction between obesity and sex hormones on current … Continue reading Sex Steroid #Hormones and #Asthma in a Nationwide Study of U.S. Adults

Δ9-tetrahydrocannabinol exposure during rat pregnancy leads to symmetrical fetal growth restriction and labyrinth-specific vascular defects in the placenta

1 in 5 women report cannabis use during pregnancy, with nausea cited as their primary motivation. Studies show that (-)-△9–tetrahydrocannabinol (Δ9-THC), the major psychoactive ingredient in cannabis, causes fetal growth restriction, though the mechanisms are not well understood.. The goal of this study was to examine, in rats, the impact of maternal Δ9-THC exposure on fetal development, neonatal outcomes, and placental development.. ..Further, at E19.5 … Continue reading Δ9-tetrahydrocannabinol exposure during rat pregnancy leads to symmetrical fetal growth restriction and labyrinth-specific vascular defects in the placenta