Day: Jan 14, 2020

Cardiology, Diet

#Tea consumption and the risk of atherosclerotic #cardiovascular disease and all-cause mortality: The China-PAR project

..Compared with never or non-habitual tea drinkers, the hazard ratio and 95% confidence interval among habitual tea drinkers was 0.80 (0.75–0.87), 0.78 (0.69–0.88), and 0.85 (0.79–0.90) for atherosclerotic cardiovascular disease incidence, atherosclerotic cardiovascular disease mortality, and all-cause mortality, respectively. Habitual tea drinkers had 1.41 years longer of atherosclerotic cardiovascular disease-free years and 1.26 years longer of life expectancy at the index age of 50 years. … Continue reading #Tea consumption and the risk of atherosclerotic #cardiovascular disease and all-cause mortality: The China-PAR project

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Diet, Gastroenterology, Infectivology

T cell receptor cross-reactivity between gliadin and #bacterial peptides in #celiac disease

The human leukocyte antigen (HLA) locus is strongly associated with T cell-mediated autoimmune disorders. HLA-DQ2.5-mediated celiac disease (CeD) is triggered by the ingestion of gluten, although the relative roles of genetic and environmental risk factors in CeD is unclear. Here we identify microbially derived mimics of gliadin epitopes and a parental bacterial protein that is naturally processed by antigen-presenting cells and activated gliadin reactive HLA-DQ2.5-restricted … Continue reading T cell receptor cross-reactivity between gliadin and #bacterial peptides in #celiac disease

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