#Skin barrier damage after exposure to para-phenylenediamine

p-Phenylenediamine (#PPD) is a strong contact allergen used in hair dye known to cause allergic contact dermatitis (ACD). Both private and occupational exposure to PPD is frequent, but the effect of PPD exposure in non-allergic occupational exposed individuals is unknown.. ..RNA-sequencing demonstrated down-regulation of tight junction (TJ) and stratum corneum (SC) proteins in skin of severe ACD patients after PPD exposure. Claudin-1 (CLDN1), claudin-8 (CLDN8), … Continue reading #Skin barrier damage after exposure to para-phenylenediamine

Association between #dairy product consumption and #hyperuricemia in an elderly population with metabolic syndrome

The prevalence of hyperuricemia has increased substantially in recent decades. It has been suggested that it is an independent risk factor for weight gain, hypertension, hypertriglyceridemia, metabolic syndrome (#MetS), and cardiovascular disease.. ..Participants in the upper quartile of the consumption of total dairy products (multiadjusted prevalence ratio (PR) = 0.84; 95% CI: 0.75–0.94; P-trend 0.02), low-fat dairy products (PR = 0.79; 95% CI: 0.70–0.89; P-trend … Continue reading Association between #dairy product consumption and #hyperuricemia in an elderly population with metabolic syndrome