Association Between #Beverage Intake and Incidence of Gastroesophageal #Reflux Symptoms

..Patients are frequently advised to eliminate coffee, tea, and/or soda to reduce symptoms of gastroesophageal reflux (GER), such as heartburn or regurgitation.

..After multivariable adjustment, hazard ratios (HRs) for women with the highest intake of each beverage (more than 6 servings/day) compared to women with the lowest intake (0 servings/day) were 1.34 for coffee (95% CI, 1.13–1.59; Ptrend<.0001), 1.26 for tea (95% CI, 1.03–1.55; Ptrend<.001), and 1.29 for soda (95% CI, 1.05–1.58; Ptrend<.0001). We obtained similar results when we stratified patients according to caffeine status. No association was observed between milk, water, or juice consumption and risk for GER symptoms. In a substitution analysis, replacement of 2 servings/day of coffee, tea, or soda with 2 servings of water was associated with reduced risk of GERD symptoms: coffee HR, 0.96 (95% CI, 0.92–1.00); tea HR, 0.96 (95% CI, 0.92–1.00); and soda HR, 0.92 (95% CI, 0.89– 0.96).

In an analysis of data from the prospective Nurses’ Health Study II, intake of coffee, tea, or soda was associated with an increased risk of GER symptoms. In contrast, consumption of water, juice, or milk were not associated with GER symptoms. Drinking water instead of coffee, tea, or soda reduced the risk of GER symptoms.