Impact of dietary #sucrose on #adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion: liquid or solid

..Since in humans consumption of sugar-sweetened beverages has been widely implicated, we investigated whether the mode of ingestion (solid or liquid) had different impacts on body weight regulation and glucose homeostasis Consumption of sucrose-sweetened water, but not equivalent levels of solid sucrose, led to body fat gain in C57BL/6 mice. Glucose intolerance was positively correlated to body fatness, rather than sucrose intake. Conclusions Our data … Continue reading Impact of dietary #sucrose on #adiposity and glucose homeostasis in C57BL/6J mice depends on mode of ingestion: liquid or solid

Effects of #tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic #brain injury (CRASH-3): a randomised, placebo-controlled trial

Tranexamic acid reduces surgical bleeding and decreases mortality in patients with traumatic extracranial bleeding. Intracranial bleeding is common after traumatic brain injury (TBI) and can cause brain herniation and death. We aimed to assess the effects of tranexamic acid in patients with TBI. The risk of head injury-related death reduced with tranexamic acid in patients with mild-to-moderate head injury (RR 0·78 [95% CI 0·64–0·95]) but … Continue reading Effects of #tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic #brain injury (CRASH-3): a randomised, placebo-controlled trial